| Entry |
|
|---|
| Name |
Milnacipran (INN) |
|---|
| Formula |
C15H22N2O
|
|---|
| Exact mass |
246.1732
|
|---|
| Mol weight |
246.348
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
|
|---|
| Remark |
| Product (DG00960): | D01107<JP/US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Comment |
selective serotonin norepinephrine reuptake inhibitor (SNRI)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX17 Milnacipran
D08222 Milnacipran (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
DG00960 Milnacipran
D08222 Milnacipran
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D08222 Milnacipran (INN)
SLC6A4 (HTT)
D08222 Milnacipran (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
DG00960 Milnacipran
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 C8x C 20.5100 -15.7500
2 C8x C 20.5100 -17.1500
3 C8x C 21.7000 -17.8500
4 C8y C 22.9600 -17.1500
5 C8x C 22.9600 -15.7500
6 C8x C 21.7000 -15.0500
7 C5a C 24.3600 -17.1500
8 C1x C 22.9600 -19.6000
9 C1y C 24.3600 -19.6000
10 C1z C 23.6600 -18.3400
11 C1b C 25.0600 -20.7900
12 O5a O 24.3600 -15.7500
13 N1c N 25.7600 -17.1500
14 C1b C 26.4600 -15.9600
15 C1b C 26.4600 -18.3400
16 C1a C 27.8600 -18.3400
17 C1a C 27.8600 -15.9600
18 N1a N 26.4600 -20.7900
BOND 19
1 8 10 1
2 10 9 1
3 3 4 2
4 9 11 1 #Up
5 10 4 1 #Down
6 10 7 1
7 4 5 1
8 7 12 2
9 5 6 2
10 7 13 1
11 6 1 1
12 13 14 1
13 13 15 1
14 15 16 1
15 1 2 2
16 14 17 1
17 2 3 1
18 11 18 1
19 8 9 1
|
|---|
